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Antigenic Specificity | Mouse NK1.1 |
Clone | [PK136] |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-gamma production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |
Immunogen | n/a |
Other Names | [Mouse NK1.1; Killer cell lectin-like receptor subfamily B member 1C; Klrb1c; CD161 antigen-like family member C; Ly-55c; NK1.1; NKR-P1.9; NKR-P1C; NKR-P1 40; CD161c] |
Gene, Accession # | [NK1.1], Gene ID: 17059, NCBI: NP_001153376.1, UniProt: P27814 |
Catalog # | MBS2553683 |
Price | $60, $70 |
Order / More Info | Mouse NK1.1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Lanier LL. 1997. Immunity 6:371. 2. Yokoyama WM, et al. 1993. Ann. Rev. Immunol. 11:613. 3. Koo GC, et al. 1986. J. Immunol. 137:3742. 4. Giorda R, et al. 1991. J. Immunol. 147:1701. |