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Antigenic Specificity | Bcl-rambo |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-rambo Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A novel, widely expressed member termed Bcl-rambo was recently identified. This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2. Bcl-rambo shows overall homology to the anti-a |
Immunogen | Immunogen: Bcl-rambo antibody was raised against a 15 amino acid synthetic peptide from near the center of human Bcl-rambo. Buffer: Bcl-rambo Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Bcl-rambo; MIL1; BCL-RAMBO; Bcl2-L-13; MIL1; CD003; Bcl-2-like protein 13; Bcl-rambo; BCL2-like 13 (apoptosis facilitator)], [BCL2L13; BCL2L13; MIL1; BCL-RAMBO; Bcl2-L-13; MIL1; Bcl2-L-13] |
Gene, Accession # | [BCL2L13], Gene ID: 23786, NCBI: AAH07658, UniProt: Q9BXK5 |
Catalog # | MBS151034 |
Price | $375 |
Order / More Info | Bcl-rambo Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |