Human Fas Ligand Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Fas Ligand |
| Clone | [SB93a1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunoprecipitation; Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reacts with native and recombinant human Fas Ligand1. Fas Ligand (CD178) is a 40 kD type II transmembrane protein that is a member of the tumor necrosis factor superfamily. This well characterized potent apoptotic factor is utilized by cytotoxic T cells and natural killer cells to selectively kill virus infected and tumorigenic cells2,3. Moreover, studies indicate that Fas Ligand is an important regulator in immune homeostasis where it has been shown to down-regulate immune responses during activation-induced cell death4. Fas Ligand initiates apoptosis by binding to its receptor (CD95) on target cells which facilitates recruitment of numerous signaling proteins to form a death inducing signaling complex. This signaling complex is then belie |
| Immunogen | Immunogen: Recombinant human Fas Ligand |
| Other Names | [Mouse Human Fas Ligand - Purified, Unlabeled; Mouse Human Fas Ligand (CD178)], [FASLG; FASLG; FASL; CD178; CD95L; CD95-L; TNFSF6; APT1LG1; APT1LG1; CD95L; FASL; TNFSF6] |
| Gene, Accession # | Gene ID: 356, UniProt: P48023 |
| Catalog # | MBS670167 |
| Price | $230 |
| Order / More Info | Human Fas Ligand Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Trambas, C.M. and Griffiths, G.M. (2003) Nat. Immunol. 4:399-403.3) Voss, M. et al. (2008). Cell. Commun. Signal. 6:11.4) Krammer, P.H. (2000). Nature. 407:789-95.5) Peter, M.E. and Krammer, P.H. (2002). Cell. Death Diff. 10:26-35. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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