TIMP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTIMP1
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsImmunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionMetalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
ImmunogenImmunogen: A synthesized peptide derived from human TIMP1. Subcellular Localization: Secreted. Tissue Specificity: Detected in rheumatoid synovial fluid (at protein level).
Other Names[Metalloproteinase inhibitor 1; Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1; TIMP1; CLGI; TIMP], [TIMP1; TIMP1; EPA; EPO; HCI; CLGI; TIMP; TIMP-1; CLGI; TIMP; EPA; Collagenase inhibitor; TIMP-1]
Gene, Accession #[TIMP1], Gene ID: 7076, NCBI: NP_003245.1, UniProt: P01033
Catalog #MBS179369
Price$160, $340, $340
Order / More InfoTIMP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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