UNC5B Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | UNC5B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion (By similarity). Functions as netrin receptor that negatively regulates vascular branching during angiogenesis. Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin (By similarity). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:12598906). Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-3 |
| Immunogen | Immunogen: Recombinant Human Netrin receptor UNC5B protein (404-517AA) |
| Other Names | [Netrin receptor UNC5B; Protein unc-5 homolog 2; Protein unc-5 homolog B; p53-regulated receptor for death and life protein 11; UNC5B; P53RDL11 Publication] |
| Gene, Accession # | [UNC5B], Gene ID: 219699, NCBI: NP_001231818.1, UniProt: Q8IZJ1 |
| Catalog # | MBS7108139 |
| Price | $160, $235 |
| Order / More Info | UNC5B Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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