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Antigenic Specificity | GAPDH |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat, porcine, zebrafish, cow, sheep, rabbit, goat, guinea pig, dog, monkey, hamster, chicken, plants, rice, fish |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GAPDH Mouse Monoclonal antibody detects endogenous levels of total GAPDH protein. Description: Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. GAPDH is constitutively abundant expressed in almost cell types at high levels, therefore antibodies against GAPDH are useful as loading controls for Western Blotting. Some pathology factors, such as hypoxia and diabetes, increased or decreased GAPDH expression in certain cell types.Function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA repl |
Immunogen | Immunogen: Full-length GAPDH protein of human. Subcellular Location: Cytoplasm > Cytosol. Nucleus. Cytoplasm > Perinuclear Region. Membrane. Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions. |
Other Names | [GAPDH; A1 40 kd subunit; Activator 1 40 kd subunit; G3PD; GAPD; G3pdh; Rfc40; Rf-c 40 kd subunit] |
Gene, Accession # | [GAPDH], Gene ID: 2597, NCBI: NP_001243728.1, UniProt: P04406 |
Catalog # | MBS9610317 |
Price | $170, $225, $280 |
Order / More Info | GAPDH Antibody from MYBIOSOURCE INC. |
Product Specific References | Lian J, Chen J, Yuan Y, Chen J, Daud M Sayed M, Luo L, Zhu Y, Li S, Bu S; Journal: Biomed Pharmacother. Cortex Mori Radicis extract attenuates myocardial damages in diabetic rats by regulating ERS. Tian YM, Guan Y, Li N, Ma HJ, Zhang L, Wang S, Zhang Y; Journal: Diabetes Res Clin Pract. Chronic intermittent hypobaric hypoxia ameliorates diabetic nephropathy through enhancing HIF1 signaling in rats. Liu S, Zheng Z, Ji S, Liu T, Hou Y, Li S, Li G; Journal: Fish Shellfish Immunol. Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-kB pathway in gut of the annual fish Nothobranchius guentheri. Wen-BingHu, JingZhao, HuiChen, LeiXiong, Wen-JunWang; Journal: J FUNCT FOODS. Polysaccharides from Cyclocarya paliurus: Chemical composition and lipid-lowering effect on rats challenged with high-fat diet. J.-H.Li, L.-Q.Qiu, X.-J.Zhu, C.-X.Cai; Journal: SCI SPORT. Influence of exercises using different energy metabolism systems on NNMT expression in different types of skeletal muscle fibers. |