TXK Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-TXK antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | TXK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence/Immunocytochemistry (IF/ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TXK antibody detects endogenous levels of total TXK. Function: Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420. Phosphorylation leads to TXK full activation. Contributes also to signaling from many receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Like ITK, can phosphorylate PLCG1, leading to its localization in li |
| Immunogen | Immunogen: A synthesized peptide derived from human TXK Subcellular Location: Cytoplasm. Nucleus. Cell Membrane. Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation. Translocates into the nucleus and enhances IFN-gamma gene transcription in T-cells. Tissue Specificity: Expressed in T-cells and some myeloid cell lines. Expressed in Th1/Th0 cells with IFN-gamma-producing potential. |
| Other Names | [BTKL; EC 2.7.10.2; MGC22473; Protein-tyrosine kinase 4; PSCTK5; PTK4; Resting lymphocyte kinase; RLK; TKL; TXK; TXK tyrosine kinase; TXK_HUMAN; Tyrosine protein kinase TXK; Tyrosine-protein kinase TXK] |
| Gene, Accession # | [TXK], Gene ID: 7294, NCBI: NP_003319.2, UniProt: P42681 |
| Catalog # | MBS9603004 |
| Price | $240, $280 |
| Order / More Info | TXK Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies