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Antigenic Specificity | PHAP I |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This polyclonal antibody has no cross-reaction to PHAP I2a and PHAP III. Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to |
Immunogen | Immunogen Type: Peptide Immunogen Description: PHAP I antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP I. This sequence is identical between human and rat PHAP I. |
Other Names | [acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; Acidic nuclear phosphoprotein pp32; pp32; Leucine-rich acidic nuclear protein; LANP; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Putative HLA-DR-associated protein I; PHAPI] |
Gene, Accession # | [PHAP I], Gene ID: 8125, NCBI: NP_006296.1, UniProt: P39687 |
Catalog # | MBS9407264 |
Price | $320 |
Order / More Info | PHAP I Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |