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Antigenic Specificity | GRB10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Growth factor receptor-bound protein 10 (GRB10) is an adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. GRB10 has three consensus domains including pleckstrin homology (PH) domain, SH2/SH3 domain and Ras-associating domain. By binding to kinases, GRB10 suppresses signals from activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. It may play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. |
Immunogen | Immunogen: Recombinant protein of human GRB10 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [GRB-IR; Grb-10; IRBP; KIAA0207; MEG1; RSS] |
Gene, Accession # | [GRB10], Gene ID: 2887, NCBI: NP_001001549.1, UniProt: Q13322 |
Catalog # | MBS8527341 |
Price | $310 |
Order / More Info | GRB10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |