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Antigenic Specificity | RAB5A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using RAB5A antibody. Immunofluorescence analysis of HeLa cell using RAB5A antibody. Blue: DAPI for nuclear staining. Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis (1). The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis (1, 2). Rab5 exerts its function by interacting with several Rab5-specific effectors (1-3). These proteins form complexes with Rab5 on a specialized Rab domain of the endosome and promote re |
Immunogen | Immunogen: Recombinant protein of human RAB5A |
Other Names | [RAB5A; Ras-related protein Rab-5A; ras-related protein Rab-5A; RAB5A, member RAS oncogene family], [RAB5A; RAB5A; RAB5; RAB5] |
Gene, Accession # | [RAB5A], Gene ID: 5868, NCBI: CAG38731.1 |
Catalog # | MBS419587 |
Price | $385 |
Order / More Info | RAB5A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |