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Antigenic Specificity | Phospho-STAT3 (Y705) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, porcine, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.88 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This STAT3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y705 of human STAT3. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes s |
Immunogen | n/a |
Other Names | [Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF] |
Gene, Accession # | [STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763 |
Catalog # | MBS9211200 |
Price | $165, $370 |
Order / More Info | Phospho-STAT3 (Y705) Antibody from MYBIOSOURCE INC. |
Product Specific References | Schick, N., et al., J. Biol. Chem. 279(37):38787-38796 (2004). Wang, H., et al., Lab. Invest. 84(8):941-951 (2004). Kato, T., et al., J. Biol. Chem. 279(30):31076-31080 (2004). Ivanova, A.V., et al., J. Mol. Biol. 340(4):641-653 (2004). Park, J., et al., Biochem. Biophys. Res. Commun. 320(1):279-285 (2004). |