Human SETD7 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human SETD7 |
| Clone | [2967C2a] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 100 ug/ml (1.0 ml) |
| Applications | Dot Blot (DB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Al |
| Immunogen | n/a |
| Other Names | [Homo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7), mRNA.; FLJ21193; KIAA1717; KMT7; SET7], [SETD7; SETD7; KMT7; SET7; SET9; SET7/9] |
| Gene, Accession # | [SETD7], Gene ID: 80854, NCBI: NP_085151.1 |
| Catalog # | MBS120560 |
| Price | $395 |
| Order / More Info | Human SETD7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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