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Antigenic Specificity | Nanog |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Nanog protein. Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed, promotes cells to |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.137~141 (K-Q-V-K-T) derived from Nano g |
Other Names | [Homeobox transcription factor Nanog] |
Gene, Accession # | [Nanog], Gene ID: 79923, NCBI: NP_001284627.1, UniProt: Q9H9S0 |
Catalog # | MBS9405875 |
Price | $200, $255 |
Order / More Info | Nanog Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |