Edit |   |
Antigenic Specificity | Phospho-Ser31 Tyrosine Hydroxylase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~60k tyrosine hydroxylase protein phosphorylated at Ser31. Affinity purified rabbit polyclonal antibody |
Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding phospho-Ser31 of rat tyrosine hydroxylase (TH). Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser31 conjugated to KLH. Immunogen Species: Rat |
Other Names | [tyrosine 3-monooxygenase; Tyrosine 3-monooxygenase; tyrosine 3-monooxygenase; tyrosine 3-hydroxylase; tyrosine hydroxylase; Tyrosine 3-hydroxylase], [Th; Th; The; TH] |
Gene, Accession # | [TH], Gene ID: 25085, NCBI: NP_036872.1, UniProt: P04177 |
Catalog # | MBS502133 |
Price | $360 |
Order / More Info | Phospho-Ser31 Tyrosine Hydroxylase Antibody from MYBIOSOURCE INC. |
Product Specific References | • Dunkley PR, Bobrovskaya L, Graham ME, Von Nagy-Felsobuki EI, Dickson PW (2004) Tyrosine hydroxylase phosphorylation: regulation and consequences. J Neurochem 91:1025-1043.• Haycock JW, Ahn NG, Cobb MH, Krebs EG (1992) ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. Proc Natl Acad Sci (USA) 89:2365-2369.• Haycock JW, Bennett WF, George RJ, Waymire JC (1982) Multiple site phosphorylation of tyrosine hydroxylase. Differential regulation in situ by a 8-bromo-cAMP and acetylcholine. J Biol Chem 257:13699-13703• Jedynak JP, Ali SF, Haycock JW, Hope BT (2002) Acute administration of cocaine regulates the phosphorylation of serine-19,-31 and-40 in tyrosine hydroxylase. J Neurochem 82:382-388.• Kish SJ, Kalasinsky KS, Derkach P, Schmunk GA, Guttman M, Ang L, Adams V, Furukawa Y, Haycock JW (2001) Striatal dopaminergic and serotonergic markers in human heroin users. Neuropsychopharmacology 24:561-567. |