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Antigenic Specificity | TNFSF12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1.93 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such |
Immunogen | Immunogen: Recombinant protein of human TNFSF12. |
Other Names | [TNFSF12; APO3L; DR3LG; TNLG4A; TWEAK; TNF superfamily member 12] |
Gene, Accession # | [TNFSF12], Gene ID: 8742, NCBI: NP_003800.1, UniProt: O43508 |
Catalog # | MBS9140861 |
Price | $260 |
Order / More Info | TNFSF12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |