ATF2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ATF2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | 1ug/ul |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ATF-2 (hosphor-Thr69 or 51) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 69 or 51. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcript |
| Immunogen | Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 69 or 51 (D-Q-TP-P-T). |
| Other Names | [ATF2 protein; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-dependent transcription factor ATF-2; activating transcription factor 2 splice variant ATF2-var2; cAMP response element-binding protein CRE-BP1; cAMP responsive element binding protein 2, formerly; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; cyclic AMP-responsive element-binding protein 2; histone acetyltransferase ATF2; activating transcription factor 2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; Histone acetyltransferase ATF2; cAMP response element-binding protein CRE-BP1], [ATF2; ATF2; HB16; CREB2; TREB7; CREB-2; CRE-BP1] |
| Gene, Accession # | [ATF2], Gene ID: 1386, NCBI: AAI07699.1 |
| Catalog # | MBS417095 |
| Price | $325 |
| Order / More Info | ATF2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sevilla A, et al. (2004) J Biol Chem. 279(26):27458-27465.Alsayed Y, et al. (2001) J Biol Chem. 276(6): 4012-4019.Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089.Gupta S, et al. (1995) Science. 267: 389-393. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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