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Antigenic Specificity | ICAD (NT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-ICAD (NT) [Rabbit antibody to peptide corresponding to aa 2-21 of mouse ICAD, inhibitor of caspase-activated Dnase.]. This antibody recognizes non-cleaved(45 kD) and cleaved ICAD. Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A human DNA fragmentation factor (DFF) that is cleaved by caspase-3 during apoptosis was identified recently. The mouse homologue of human DFF was identified as a DNase inhibitor and was designated ICAD (inhibitor of caspaseactivat |
Immunogen | Antigen: Peptide corresponding to aa2-21 at the N-terminus of mouse ICAD. |
Other Names | n/a |
Gene, Accession # | NCBI: AAN60066.1 |
Catalog # | MBS194100 |
Price | $415 |
Order / More Info | ICAD (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |