PD-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPD-1
Clone[IHC001]
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mL (Concentrate), 7 mL (Prediluted), 1 mL (Concentrate)
Concentrationn/a
Applicationsn/a
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DescriptionIntended Use: The PD-1 [IHC001] antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods. Description: Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T-cell regulators, expressed as a co-receptor on the surface of activated T-cells, B-cells, and macrophages. New studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to anti-tumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considere
Immunogenn/a
Other Names[programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; programmed cell death 1; CD_antigen: CD279], [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1]
Gene, Accession #[PD-1], Gene ID: 5133, NCBI: NP_005009.2, UniProt: Q15116
Catalog #MBS344001
Price$165, $225, $245
Order / More InfoPD-1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Dorfman DM, et al. Am J Surg Pathol. 2006; 30:802-10.2. Hamanishi J, et al. Proc Natl Acad Sci USA. 2007; 104:3360-5.3. Kobayashi M, et al. J Rheumatol. 2005; 32:2156-63.4. Konishi J, et al. Clin Cancer Res. 2004; 10:5094-100.5. Mataki N, et al. Am J Gastroenterol. 2007; 102:302-12.6. Kim JW, et al. Oncology (Williston Park). 2014; 28:15-28.7. Tumeh PC, et al. Nature. 2014; 515:568-71.8. D'Incecco A, et al. Br J Cancer. 2015; 112:95-102.9. Tykodi SS. Onco Targets Ther. 2014; 7:1349-59.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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