MEK1/2 (Non- Phosphospecific) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMEK1/2 (Non- Phosphospecific)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, chicken
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot
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DescriptionThis antibody recognizes ~44/45 kDa of human MEK1 protein without phosphorylation sites of Ser 218/222 or MEK2 (pS222/226). It does not cross react to phospho MEK1/2. This antibody also reacts with mouse and rat, chicken. The other species are not tested. The MEK1 & 2 (MAPKK1/2) are members of tyrosine/threonine protein kinase family that activate the ERK1+2/MAPK enzymes by phosphorylation. MEK 1 + 2 are also activated by dual-phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEKs. The MEK1 & 2 are regulated by phosphorylation by one of the MEK kinases.
ImmunogenAntigen Preparation: A synthetic peptide surrounding the epitope -SMANS- without phosphorylation of human MEK1/2. This sequence is identical among human, rat, mouse, chicken.
Other Namesn/a
Gene, Accession #[MEK1/2 (paired S218/S222)]
Catalog #MBS462073
Price$285
Order / More InfoMEK1/2 (Non- Phosphospecific) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAli R. Jazirehi, et al. Inhibition of the Raf-MEK1/2-ERK1/2 Signaling Pathway, Bcl-xL Down-Regulation, and Chemosensitization of Non-Hodgkin's Lymphoma B Cells by Rituximab. CANCER RESEARCH 64, 7117-7126, October 1, 2004
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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