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Antigenic Specificity | LIR-8 (Leukocyte Immunoglobulin-like Receptor 8, CD85c) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | ~0.2mg/ml (after reconstitution) |
Applications | ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human LIR-8, Shows <20% crossreactivity with rhLIR-4. ~10% with rhILT5, rhLIR-5, rhLIR-6, and rhLILRA5 amd <5% with rhILT2, rhILT4, and rhLIR-7. Human LIR-8 (also known as CD85c and LILRB5) is a 587 amino acid transmembrane protein of the family of Leukocyte Immunoglobin-like Receptors. LIR-8 has a long N-terminus extracellular domain with four C2-type lg-like domains, and a short cytoplasmic tail with two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) typically involved in modulation of cellular responses. Human LIR-8 is expressed in natural killer (NK) cells. There are at least two other known isoforms, one with 53 aa longer cytoplasmic domain, the other with a 100 aa deletion affecting one of the lg-like extracellular |
Immunogen | Immunogen: NS0-derived rhLIR-8 (aa18-456) isoform. Immunogen Information: Recombinant protein corresponding to aa 18-456 from human LIR-8, expressed in NS0 cells (O75023) |
Other Names | [-LIR-8 (Leukocyte Immunoglobulin-like Receptor 8, CD85c)], [LILRB5; LILRB5; LIR8; CD85C; LIR-8; LIR8; LIR-8] |
Gene, Accession # | Gene ID: 10990, NCBI: NP_001074912.1, UniProt: O75023 |
Catalog # | MBS610400 |
Price | $765 |
Order / More Info | LIR-8 (Leukocyte Immunoglobulin-like Receptor 8, CD85c) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |