LIR-8 (Leukocyte Immunoglobulin-like Receptor 8, CD85c) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLIR-8 (Leukocyte Immunoglobulin-like Receptor 8, CD85c)
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentration~0.2mg/ml (after reconstitution)
ApplicationsELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionRecognizes human LIR-8, Shows <20% crossreactivity with rhLIR-4. ~10% with rhILT5, rhLIR-5, rhLIR-6, and rhLILRA5 amd <5% with rhILT2, rhILT4, and rhLIR-7. Human LIR-8 (also known as CD85c and LILRB5) is a 587 amino acid transmembrane protein of the family of Leukocyte Immunoglobin-like Receptors. LIR-8 has a long N-terminus extracellular domain with four C2-type lg-like domains, and a short cytoplasmic tail with two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) typically involved in modulation of cellular responses. Human LIR-8 is expressed in natural killer (NK) cells. There are at least two other known isoforms, one with 53 aa longer cytoplasmic domain, the other with a 100 aa deletion affecting one of the lg-like extracellular
ImmunogenImmunogen: NS0-derived rhLIR-8 (aa18-456) isoform. Immunogen Information: Recombinant protein corresponding to aa 18-456 from human LIR-8, expressed in NS0 cells (O75023)
Other Names[-LIR-8 (Leukocyte Immunoglobulin-like Receptor 8, CD85c)], [LILRB5; LILRB5; LIR8; CD85C; LIR-8; LIR8; LIR-8]
Gene, Accession #Gene ID: 10990, NCBI: NP_001074912.1, UniProt: O75023
Catalog #MBS610400
Price$765
Order / More InfoLIR-8 (Leukocyte Immunoglobulin-like Receptor 8, CD85c) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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