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Antigenic Specificity | Mouse Irgm1 (C-term) |
Clone | [403CT8.5.5] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgM |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged Mouse Irgm1 protein was used to produced this monoclonal antibody. Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion. |
Immunogen | n/a |
Other Names | [Immunity-related GTPase family M protein 1; 365-; Interferon-inducible GTPase 3; Interferon-inducible protein 1; LPS-stimulated RAW 2647 macrophage protein 47; LRG-47; Irgm1; Ifi1; Iigp3; Irgm] |
Gene, Accession # | [Irgm1], Gene ID: 15944, NCBI: NP_032352.1, UniProt: Q60766 |
Catalog # | MBS9200259 |
Price | $165, $370 |
Order / More Info | Mouse Irgm1 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Dhar, N., et al. Proc. Natl. Acad. Sci. U.S.A. 107(27):12275-12280(2010) Xu, H., et al. FASEB J. 24(5):1583-1592(2010) Henry, S.C., et al. J. Leukoc. Biol. 87(2):333-343(2010) Zhao, Y.O., et al. PLoS ONE 5 (1), E8648 (2010) : Tiwari, S., et al. Nat. Immunol. 10(8):907-917(2009) |