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Antigenic Specificity | Human CD28 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CD28. CD28 is a 44 kDa homodimeric transmembrane glycoprotein and a member of the Ig-SF. It is constitutively expressed on most T-lineage cells and plasma cells. While activation of T cells leads to enhanced CD28 expression, ligation of the CD28 molecule leads to its transient downregulation. Like CD152 (CTLA-4), CD28 binds both CD80 and CD86 and plays a very important role in T cell-B cell interaction and humoral immunity. Its precise role in providing the costimulatory signal necessary for T cell activation is still under study. |
Immunogen | n/a |
Other Names | [CD28, partial; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; CD28 antigen; CD_antigen: CD28] |
Gene, Accession # | [CD28], Gene ID: 12487, NCBI: AAA37396.1 |
Catalog # | MBS4152220 |
Price | $445 |
Order / More Info | Human CD28 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |