Edit |   |
---|---|
Antigenic Specificity | Human Toll/interleukin-1 receptor domain-containing adapter protein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
Immunogen | Immunogen: Recombinant human Toll/interleukin-1 receptor domain-containing adapter protein (1-221aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19950 / sc-19952 / sc-31308 / sc-31309 / sc-28822 |
Other Names | [TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; MyD88-2; TIRAP; MAL], [TIRAP; TIRAP; Mal; wyatt; BACTS1; MyD88-2; MAL; TIR domain-containing adapter protein; MyD88-2] |
Gene, Accession # | [TIRAP], Gene ID: 114609, NCBI: NP_001034750.1, UniProt: P58753 |
Catalog # | MBS1492712 |
Price | $120, $160 |
Order / More Info | Human Toll/interleukin-1 receptor domain-containing adapter protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |