RNF20 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RNF20 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RNF20 antibody detects endogenous levels of total RNF20. Function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being re |
| Immunogen | Immunogen: A synthesized peptide derived from human RNF20 Subcellular Location: Nucleus. Tissue Specificity: Expressed in the normal brain and also in malignant gliomas (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (83%) |
| Other Names | [BRE1 A; BRE1; BRE1 E3 ubiquitin ligase homolog; BRE1-A; BRE1A; BRE1A_HUMAN; E3 ubiquitin-protein ligase BRE1A; hBRE1; Homolog of S. cerevisiae BRE1; RING finger protein 20; Ring finger protein 20 E3 ubiquitin protein ligase; Rnf20] |
| Gene, Accession # | [RNF20], Gene ID: 56254, NCBI: NP_062538.5, UniProt: Q5VTR2 |
| Catalog # | MBS9604428 |
| Price | $240, $280 |
| Order / More Info | RNF20 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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