HEF-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHEF-1
Clone[C7.16D5.2G9.3C6]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1 kappa
Formatpurified
Size0.1 mg
Concentration100ug/100ul
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionSpecificity: Specific only for HEF1, does not recognize p130Cas. Have not tested on Sin1. HEF-1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation. Experiments convey the idea that HEF1 may represent a marker for an enhanced possibility of tumor metastasis. Furthermore, HEF1 belongs to the 18 gene signature prognostic of breast cancer metastasis to lung tissue.
ImmunogenImmunogen: GST-HEF1 (82-398aa)
Other Namesn/a
Gene, Accession #[HEF-1]
Catalog #MBS418473
Price$310
Order / More InfoHEF-1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPugacheva EN, and Golemis EA, The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome, Nat. Cell Biol 2005 Sep; 7, 937 - 946 [PMID: 16184168]
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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