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Antigenic Specificity | HEF-1 |
Clone | [C7.16D5.2G9.3C6] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 kappa |
Format | purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific only for HEF1, does not recognize p130Cas. Have not tested on Sin1. HEF-1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation. Experiments convey the idea that HEF1 may represent a marker for an enhanced possibility of tumor metastasis. Furthermore, HEF1 belongs to the 18 gene signature prognostic of breast cancer metastasis to lung tissue. |
Immunogen | Immunogen: GST-HEF1 (82-398aa) |
Other Names | n/a |
Gene, Accession # | [HEF-1] |
Catalog # | MBS418473 |
Price | $310 |
Order / More Info | HEF-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pugacheva EN, and Golemis EA, The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome, Nat. Cell Biol 2005 Sep; 7, 937 - 946 [PMID: 16184168] |