Bad Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Bad |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 200 ug/ml |
| Applications | Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects 23 kDa Bad only when phosphorylated at Ser112. Bad is a member of the Bcl 2 family protein that selectively dimerize with Bcl xL and Bcl 2 resulting in cell death. Survival factors such as IL 3 can inhibit the apoptotic activity of Bad by activating intracellular signaling pathways that result in the phosphorylation of Bad at Ser112 and Ser 136. Phosphorylation at these sites results in the binding of Bad to 14 3 3 proteins and the inhibition of Bad binding to Bcl xL and Bcl 2. Recently, Akt has also been shown to promote cell survival via its ability to phosphorylate Bad at Ser136. |
| Immunogen | n/a |
| Other Names | [Rabbit Bad; Bad; Bad; Phospho-Bad] |
| Gene, Accession # | [Bad] |
| Catalog # | MBS5309083 |
| Price | $735 |
| Order / More Info | Bad Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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