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Antigenic Specificity | EpoR (Phospho Tyr426) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-EpoR (Y426) Polyclonal Antibody detects endogenous levels of EpoR protein only when phosphorylated at Y426. EPOR encodes the erythropoietin receptor (erythropoietin receptor) which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of EPOR may affect the growth of certain tumors. Alternate splicing results in multiple tra |
Immunogen | Immunogen: Synthesized peptide derived from human EpoR around the phosphorylation site of Y426 |
Other Names | [Rabbit EpoR (phospho Tyr426); EPOR; Erythropoietin receptor; EPO-R] |
Gene, Accession # | [EPOR], Gene ID: 2057, NCBI: NP_000112.1, UniProt: P19235 |
Catalog # | MBS9701277 |
Price | $130, $220, $325 |
Order / More Info | EpoR (Phospho Tyr426) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |