EpoR (Phospho Tyr426) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEpoR (Phospho Tyr426)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Phospho-EpoR (Y426) Polyclonal Antibody detects endogenous levels of EpoR protein only when phosphorylated at Y426. EPOR encodes the erythropoietin receptor (erythropoietin receptor) which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of EPOR may affect the growth of certain tumors. Alternate splicing results in multiple tra
ImmunogenImmunogen: Synthesized peptide derived from human EpoR around the phosphorylation site of Y426
Other Names[Rabbit EpoR (phospho Tyr426); EPOR; Erythropoietin receptor; EPO-R]
Gene, Accession #[EPOR], Gene ID: 2057, NCBI: NP_000112.1, UniProt: P19235
Catalog #MBS9701277
Price$130, $220, $325
Order / More InfoEpoR (Phospho Tyr426) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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