GRP78 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRP78
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG2b
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunoblot (IB)
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DescriptionThis antibody recognizes human GRP78. GRP78 is a ubiquitously expressed, 78kDa glucose-regulated protein commonly referred to as an immunoglobulin chain binding protein (BiP). Categorized as stress response proteins, BiPs play an important role in folding and assembly of nascent proteins and in scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5- nontranslated region of BiP mRNA. BiP IRES activity increases when cells are heat-stressed. GRP78 is also important in maintenance of cell omeostasis and the prevention of apoptosis. Levels of GRP78 protein are reduced in brains of Alzheimers disease patients.
ImmunogenAntigen: His-tagged human GRP78 (accession no. NP_001156906.1)
Other Names[Grp78], [HSPA5; HSPA5; BIP; MIF2; GRP78; HEL-S-89n; GRP78; GRP-78; BiP]
Gene, Accession #[GRP78], Gene ID: 3309, NCBI: AAA52614.1
Catalog #MBS190635
Price$335
Order / More InfoGRP78 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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