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Antigenic Specificity | Myelin Basic Protein, Degraded (MBP) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes Myelin Basic Protein in demyelinated nerve tissues. High specificity for lesioned rat spinal cord. Myelin basic protein (MBP) is a single-chain, flexible polypeptide of about 18.5kD existing in its natural environment as an extrinsic and loosely bound component of the cytoplasmic portion of the myelin membrane sandwich. Ultrastructural immunocytochemistry with anti-myelin basic protein has shown that MBP is localized in the compact myelin sheath. MBP has not been demonstrated in rough endoplasmic reticulum, lysosomes or any other cytoplasmic organelles (3). MBP serves as a marker for oligodendrocytes and Schwann cells (3). MBP is also a marker for malignant schwannomas (4) and appears to play a significant role in the etiology of |
Immunogen | Immunogen: Synthetic peptide corresponding to aa69-86 of the guinea pig Myelin Basic Protein |
Other Names | [-Myelin Basic Protein, Degraded (MBP)], [Mbp; Mbp; Mbps] |
Gene, Accession # | Gene ID: 24547, NCBI: NP_001020465.1, UniProt: P02688 |
Catalog # | MBS618031 |
Price | $690 |
Order / More Info | Myelin Basic Protein, Degraded (MBP) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |