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Antigenic Specificity | Phospho-Bid (S65) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.4 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Bid Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S65 of human Bid. Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. Bid induces ICE-like proteases and apoptosis. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the major proteolytic product p15 Bid translocates to mitochondria where it triggers cytochrome c release. |
Immunogen | n/a |
Other Names | [BH3-interacting domain death agonist; p22 BID; BID; BH3-interacting domain death agonist p15; p15 BID; BH3-interacting domain death agonist p13; p13 BID; BH3-interacting domain death agonist p11; p11 BID; BID] |
Gene, Accession # | [BID], Gene ID: 637, NCBI: NP_001187.1, UniProt: P55957 |
Catalog # | MBS9214985 |
Price | $165, $370 |
Order / More Info | Phospho-Bid (S65) Antibody from MYBIOSOURCE INC. |
Product Specific References | Liu, J., et al., Biochem. Biophys. Res. Commun. 330(3):865-870 (2005). Broaddus, V.C., et al., J. Biol. Chem. 280(13):12486-12493 (2005). Weng, C., et al., J. Biol. Chem. 280(11):10491-10500 (2005). Gong, X.M., et al., J. Biol. Chem. 279(28):28954-28960 (2004). Garcia-Saez, A.J., et al., Biochemistry 43(34):10930-10943 (2004). |