MAGI3 (C-Term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAGI3 (C-Term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis MAGI3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1330-1360 amino acids from human MAGI3. Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
Immunogenn/a
Other Names[Purified Rabbit (Pab); Membrane-associated guanylate kinase; WW and PDZ domain-containing protein 3; Membrane-associated guanylate kinase inverted 3; MAGI-3; MAGI3; KIAA1634]
Gene, Accession #[MAGI3], Gene ID: 260425, NCBI: NP_001136254.1, UniProt: Q5TCQ9
Catalog #MBS9215751
Price$165, $370
Order / More InfoMAGI3 (C-Term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWu Y.,et al.J. Biol. Chem. 275:21477-21485(2000).Franklin J.L.,et al.Exp. Cell Res. 303:457-470(2005).Gregory S.G.,et al.Nature 441:315-321(2006).Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.Nagase T.,et al.DNA Res. 7:273-281(2000).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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