Edit |   |
---|---|
Antigenic Specificity | HP-1alpha |
Clone | [7B6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein A purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Immunogen | Immunogen: Recombinant Protein of HP-1alpha Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.4 Conjugation: Unconjugated |
Other Names | [Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)] |
Gene, Accession # | [HP-1alpha], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973 |
Catalog # | MBS2548922 |
Price | $110, $150, $225 |
Order / More Info | HP-1alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |