APG12 / ATG12 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAPG12 / ATG12
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: Autophagy, the process of bulk degradation of cellular proteins thromugh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) thromugh phosphorylation of autophagy protein APG1. ATG12, another member of the autophagy protein family, forms a conjmugate with ATG5; this conjmugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjmugate also associates with innate immune response proteins such as RIG-I and VISA (also known as
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 21 of mouse APG12
Other Names[APG12; APG12L; ATG12; HAPG12], [Atg12; Atg12; Apg12l; Atg12l; 4931423H11Rik; A330058M13Rik; Apg12; Apg12l; APG12-like]
Gene, Accession #[APG12/ATG12], Gene ID: 67526, NCBI: NP_080493.2, UniProt: Q9CQY1
Catalog #MBS841012
Price$150, $290
Order / More InfoAPG12 / ATG12 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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