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Antigenic Specificity | ROBO4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.4 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ROBO4 protein. Robo4 (roundabout homolog 4 or magic roundabout) is a receptor for Slit proteins which implicate in angiogenesis and vascular patterning especially through facilitating inhibition of primary endothelial cell migration. It is a fairly recently identified member of Robo family and is shorter than other Robo members at both intracellular as well as extracellular domains. Robo4 plays important roles in several aspects of vascular development such as the guidance of endothelial cell migration, cell cycle regulation, inhibition of pathologic angiogenesis and endothelial hyperpermeability etc. Employing mouse and zebrafish models, Slit2/Robo4 interactions have been shown to maintain in |
Immunogen | Immunogen Type: Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human roundabout, axon guidance receptor, homolog 4 (Drosophila) |
Other Names | [MRB; ECSM4] |
Gene, Accession # | [ROBO4], Gene ID: 54538, NCBI: NP_001288017.1, UniProt: Q8WZ75 |
Catalog # | MBS9402088 |
Price | $255 |
Order / More Info | ROBO4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |