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Antigenic Specificity | VISA - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against VISA. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI (ROBO3). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK) and IKKB (IKBKB), which activate NFKB, or TBK1 and IKKE (IKBKE), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNB (IFNB1). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1). For RIGI, th |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VISA |
Other Names | [mitochondrial antiviral-signaling protein isoform 1; mitochondrial antiviral-signaling protein; mitochondrial antiviral signaling protein] |
Gene, Accession # | [MAVS], Gene ID: 57506, NCBI: NP_065797, UniProt: Q2HWT5 |
Catalog # | MBS3209515 |
Price | $335 |
Order / More Info | VISA - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |