BRCA1 (N-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBRCA1 (N-TERMINAL)
Clone[BR64]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatunconjugated
Size0.05 mg
ConcentrationIgG concentration 1.0 mg/ml
ApplicationsImmunoprecipitation (IP), Western Blot (WB)
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DescriptionMouse anti Human BRCA1 antibody, clone BR64 recognizes an epitope within the100 amino acid N-Terminal (NT) regionof human BRCA1, otherwise known as breast cancer type 1 susceptibility protein, a tumor suppressor gene and major player in DNA damage repair, predominantly expressed in the nucleus during the S/G2 phase of the cell cycle.Along with BRCA2, BRCA1 is a high risk gene which is associated with hereditary breast and ovarian cancers, particularly at a younger age of diagnosis. Women carrying the BRCA1 mutation have a 50-95% chance of developing breast cancer in later life, but genetic screening and increased awareness of preventative surgery, can reduce this risk significantly. Deleterious BRCA1 mutations may also increase the risk of
Immunogenn/a
Other Names[BRCA1; Breast cancer type 1 susceptibility protein; breast cancer type 1 susceptibility protein; BRCA1/BRCA2-containing complex, subunit 1; Fanconi anemia, complementation group S; RING finger protein 53; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; protein phosphatase 1, regulatory subunit 53; breast cancer 1, early onset; RING finger protein 53], [BRCA1; BRCA1; IRIS; PSCP; BRCAI; BRCC1; FANCS; PNCA4; RNF53; BROVCA1; PPP1R53; RNF53]
Gene, Accession #[BRCA1], Gene ID: 672, NCBI: AAC37594.1
Catalog #MBS219921
Price$430
Order / More InfoBRCA1 (N-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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