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Antigenic Specificity | Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker) |
Clone | [A53-B/A2.26 + BA17] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 and IgG2a, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer. |
Immunogen | Immunogen: Human breast cancer MCF-7 cells (A53-B/A2); Human mammary epithelial organoids (BA17) |
Other Names | [k19; k1cs; Keratin 19 Keratin Type i 40kD; krt19], [KRT19; KRT19; K19; CK19; K1CS; CK-19; K19] |
Gene, Accession # | [KRT19], Gene ID: 3880, NCBI: NP_002267.2, UniProt: P08727 |
Catalog # | MBS438116 |
Price | $190, $340, $340 |
Order / More Info | Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Morton JP et. al. Am J Pathol 172:1081-7 (2008). Bartek J et. al. Histochemical Journal, 1990, 22(10):537-44. Olofsson MH et. al. Clin Cancer Res 13:3198-206 (2007) |