KREMEN2 (Center), 248-276 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | KREMEN2 (Center), 248-276 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2. This gene encodes a high-affinity dickkopf homolog 1(DKK1) transmembrane receptor that functionally cooperates withDKK1 to block wingless (WNT)/beta-catenin signaling. The encodedprotein forms a ternary membrane complex with DKK1 and the WNTreceptor lipoprotein receptor-related protein 6 (LRP6), and inducesrapid endocytosis and removal of LRP6 from the plasma membrane. Itcontains extracellular kringle, WSC, and CUB domains. Alternativelyspliced transcript variants encoding distinct isoforms have beenobserved for this gene. |
| Immunogen | n/a |
| Other Names | [Kremen protein 2; Dickkopf receptor 2; Kringle domain-containing transmembrane protein 2; Kringle-containing protein marking the eye and the nose; KREMEN2; KRM2] |
| Gene, Accession # | [KREMEN2], Gene ID: 79412, NCBI: NP_001240654.1, UniProt: Q8NCW0 |
| Catalog # | MBS9200821 |
| Price | $165, $370 |
| Order / More Info | KREMEN2 (Center), 248-276 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Mao, B., et al. Nature 417(6889):664-667(2002) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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