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Antigenic Specificity | CSE1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 222 and 439 of CSE1L |
Other Names | [exportin-2 isoform 1; Exportin-2; exportin-2; CSE1 chromosome segregation 1-like (yeast); Cellular apoptosis susceptibility protein; Chromosome segregation 1-like protein; Importin-alpha re-exporter] |
Gene, Accession # | [CSE1L], Gene ID: 1434, NCBI: NP_001307 |
Catalog # | MBS9407789 |
Price | $320 |
Order / More Info | CSE1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |