CD71 (C-term), 649-677 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD71 (C-term), 649-677
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionThis CD71 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 649-677 amino acids from the C-terminal region of human CD71. Cellular uptake of iron occurs via receptor mediated endocytosis of ligand occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity. A second ligand, th
Immunogenn/a
Other Names[Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD71; Transferrin receptor protein 1; serum form; sTfR; TFRC]
Gene, Accession #[TFRC], Gene ID: 7037, NCBI: NP_001121620.1, UniProt: P02786
Catalog #MBS9212244
Price$165, $370
Order / More InfoCD71 (C-term), 649-677 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesChicz,R.M., et.al., Nature 358 (6389), 764-768 (1992) Hayes,G.R., et.al., Glycobiology 2 (4), 355-359 (1992)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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