NANOG Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NANOG |
| Clone | [60CT77.1.1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,k |
| Format | unconjugated |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.25 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This NANOG monoclonal antibody is generated from mouse immunized with NANOG recombinant protein. Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarit |
| Immunogen | n/a |
| Other Names | [Homeobox protein NANOG; Homeobox transcription factor Nanog; hNanog; NANOG] |
| Gene, Accession # | [NANOG], Gene ID: 79923, NCBI: NP_079141.2, UniProt: Q9H9S0 |
| Catalog # | MBS9200080 |
| Price | $165, $370 |
| Order / More Info | NANOG Antibody from MYBIOSOURCE INC. |
| Product Specific References | Trubiani, O., et al. J. Cell. Physiol. 225(1):123-131(2010) Po, A., et al. EMBO J. 29(15):2646-2658(2010) Zbinden, M., et al. EMBO J. 29(15):2659-2674(2010) Moretto-Zita, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(30):13312-13317(2010) Kuijk, E.W., et al. PLoS ONE 5 (6), E10987 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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