H2AFX (C-term), 115-143 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-H2AFX (C-term), 115-143 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | H2AFX (C-term), 115-143 |
| Clone | [938CT5.1.1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This H2AFX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the C-terminal region of human H2AFX. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ion |
| Immunogen | n/a |
| Other Names | [Histone H2AX; H2a/x; Histone H2AX; H2AFX; H2AX] |
| Gene, Accession # | [H2AFX], Gene ID: 3014, NCBI: NP_002096.1, UniProt: P16104 |
| Catalog # | MBS9200198 |
| Price | $165, $370 |
| Order / More Info | H2AFX (C-term), 115-143 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Stewart G.S., et al. Nature 421:961-966(2003). Park E.-J., et al. Nucleic Acids Res. 31:6819-6827(2003). Stiff T., et al. Cancer Res. 64:2390-2396(2004). Lukas C., et al. EMBO J. 23:2674-2683(2004). Kurz E.U., et al. J. Biol. Chem. 279:53272-53281(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies