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Antigenic Specificity | WNK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: WNK3 antibody detects endogenous levels of total WNK3. Description: This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.Function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodiu |
Immunogen | Immunogen: A synthesized peptide derived from human WNK3 Tissue Specificity: Expressed in brain, lung, kidney, liver and pancreas, and in fetal tissues including placenta, fetal brain, lung and kidney. Very low levels of expression were also detected in fetal heart, thymus, liver and spleen. Isoform 1 is brain-specific. Isoform 3 is kidney-specific. Predicted Cross Reactivity: Pig, Horse, Rabbit, Dog Similarity: Pig (100%), Horse (100%), Rabbit (100%), Dog (100%) |
Other Names | [KIAA1566; PRKWNK 3; PRKWNK3; Protein kinase lysine deficient 3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3; Serine/threonine protein kinase WNK3; Serine/threonine-protein kinase WNK3; WNK 3; WNK lysine deficient protein kinase 3; Wnk3; WNK3_HUMAN] |
Gene, Accession # | [WNK3], Gene ID: 65267, NCBI: NP_001002838.1, UniProt: Q9BYP7 |
Catalog # | MBS9608044 |
Price | $240, $280 |
Order / More Info | WNK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |