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Antigenic Specificity | Human CALCRL / CGRP Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Gibbon, bovine, dog, Xenopus, gorilla, goat, hamster, horse, human, monkey, orangutan, porcine, rabbit, rat. predicted reactivity: mouse, bat, guinea pig, zebrafish (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CALCRL. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CALCR (56%). Calcitonin receptor-like receptor (CRLR) is an Adrenomedullin Receptor that requires two additional proteins to function: a chaperone protein RAMP (receptor activity modifying protein) and the component protein RCP. The function of CRLR depends on its interaction with RAMP. When coexpressed with RAMP1, CRLR acts as a receptor for calcitonin gene-related peptide (CGRP). In contrast, when CRLR is coexpressed with either RAMP2 or RAMP3, it acts as a receptor for adrenomedullin. |
Immunogen | Immunogen Description: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CALCRL. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Rat, Goat, Hamster, Panda, Dog, Bovine, Horse, Rabbit, Pig. |
Other Names | [CALCRL / CGRP Receptor (Cytoplasmic Domain) IHC-plus; CALCRL; CGRP type 1 receptor; Cgrp1 receptor; CRLR; Calcitonin receptor-like; CGRP receptor; CGRPR; Human CALCRL; CGRP Receptor], [CALCRL; CALCRL; CRLR; CGRPR; CGRPR; CGRP type 1 receptor] |
Gene, Accession # | [CALCRL], Gene ID: 10203, NCBI: NP_005786.1, UniProt: Q16602 |
Catalog # | MBS242798 |
Price | $530 |
Order / More Info | Human CALCRL / CGRP Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |