POLK (Center), 531-560 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | POLK (Center), 531-560 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This POLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the Central region of human POLK. External and internal DNA-damaging agents continuallythreaten the integrity of genetic material in cells. Although avariety of repair mechanisms exist to remove the resulting lesions,some lesions escape repair and block the replication machinery.Members of the Y family of DNA polymerases, such as POLK, permitthe continuity of the replication fork by allowing replicationthrough such DNA lesions. Each Y family polymerase has a uniqueDNA-damage bypass and fidelity profile. POLK is specialized for theextension step of lesion bypass (summary by Lone et al |
| Immunogen | n/a |
| Other Names | [DNA polymerase kappa; DINB protein; DINP; POLK; DINB1] |
| Gene, Accession # | [POLK], Gene ID: 51426, NCBI: NP_057302.1, UniProt: Q9UBT6 |
| Catalog # | MBS9213419 |
| Price | $165, $370 |
| Order / More Info | POLK (Center), 531-560 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press : Katafuchi, A., et al. Nucleic Acids Res. 38(3):859-867(2010) Fukuda, H., et al. J. Biol. Chem. 284(38):25585-25592(2009) Irimia, A., et al. J. Biol. Chem. 284(33):22467-22480(2009) |
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MYBIOSOURCE INC.
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