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Antigenic Specificity | CASP8AP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CASP8AP2 protein. This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human caspase 8 associated protein 2 |
Other Names | [CED-4; FLASH; RIP25] |
Gene, Accession # | [CASP8AP2], Gene ID: 9994, NCBI: NP_001131139.1, UniProt: Q9UKL3 |
Catalog # | MBS9408935 |
Price | $255 |
Order / More Info | CASP8AP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |