PINK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPINK1
Clone[S4-15]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatAPC-Cy7 conjugate
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionDetects ~50 kDa. PINK1 (PTEN induced putative kinase 1) is a mitochondrial serine/threonine kinase which maintains mitochondrial function/integrity, provides protection against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins, and is involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). PINK1 is synthesized as a 63 kD protein which undergoes proteolyt processing to generate at least two cleaved forms (55 kD and 42 kD). PINK1 and its substrates have been found in the cytosol as well as in different sub-mitochondrial compartments, and according to the recent reports; PINK1 may be targeted to OMM (outer mitochondrial membrane) with its kinase domain facing
ImmunogenImmunogen: Fusion protein amino acids 112-496 (cytoplasmic C-terminus) of human PINK1. 82% identical to rat and 81% identical to mouse. >30% identity with DMPK.
Other Names[Mouse Human PINK1 IgG1; PINK1 : APC/Cy7; Parkinson disease (autosomal recessive) 6; EC 2.7.11.1; PARK6; serine/threonine-protein kinase PINK1 mitochondrial; PTEN-induced putative kinase protein 1; protein kinase BRPK; BRPK; FLJ27236; PTEN induced putative kinase 1; Phosphatase and Tensin Homolog]
Gene, Accession #[PINK1], Gene ID: 65018, NCBI: NP_115785.1, UniProt: Q9BXM7
Catalog #MBS8003394
Price$510
Order / More InfoPINK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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