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Antigenic Specificity | Claudin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Claudin 1 antibody detects endogenous levels of total Claudin 1. Description: Claudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Acts as a co-receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo-and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins.Function: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essentia |
Immunogen | Immunogen: A synthesized peptide derived from human Claudin 1 Subcellular Location: Cell Junction, Tight Junction. Cell Membrane. Tissue Specificity: Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis. |
Other Names | [Claudin-1; Claudin1; CLD 1; CLD1; CLD1_HUMAN; CLDN 1; Cldn1; ILVASC; SEMP 1; SEMP1; Senescence associated epithelial membrane protein 1; Senescence associated epithelial membrane protein; Senescence-associated epithelial membrane protein] |
Gene, Accession # | [CLDN1], Gene ID: 9076, NCBI: NP_066924.1, UniProt: O95832 |
Catalog # | MBS9600065 |
Price | $240, $280 |
Order / More Info | Claudin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |