Human XIAP Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human XIAP antibody, protein, ELISA kits.
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| Antigenic Specificity | Human XIAP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The inhibitor of apoptosis protein (IAP) family consists of an evolutionarily conserved group of apoptosis inhibitors containing a conserved 70 amino acid BIR (baculovirus inhibitor repeat) domain (1,2). Human members of this family include c-IAP1, c-IAP2, XIAP, survivin, livin, and NAIP. Overexpression of IAP family members, particularly survivin and livin, in cancer cell lines and primary tumors suggests an important role for these proteins in cancer progression (3-5). In general, the IAP proteins function through direct interactions to inhibit the activity of several caspases, including caspase-3, caspase-7, and caspase-9 (5,6). In addition, binding of IAP family members to the mitochondrial protein Smac blocks their interaction with cas |
| Immunogen | Immunogen: A fusion protein of human XIAP |
| Other Names | [XIAP Rabbit pab], [XIAP; API3; BIRC4; ILP1; MIHA; XLP2] |
| Gene, Accession # | [XIAP], Gene ID: 331, NCBI: NP_001158.2, UniProt: P98170 |
| Catalog # | MBS125431 |
| Price | $275, $430, $655 |
| Order / More Info | Human XIAP Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Deveraux, Q.L. and Reed, J.C. (1999) Genes Dev 13, 239-52.2. Deveraux, Q.L. et al. (1998) EMBO J 17, 2215-23.3. Altieri, D.C. et al. (1999) Lab Invest 79, 1327-33.4. Tamm, I. et al. (2000) Clin Cancer Res 6, 1796-803.5. Kasof, G.M. and Gomes, B.C. (2001) J Biol Chem 276, 3238-46. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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