RNA Polymerase II/Poll II Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RNA Polymerase II/Poll II |
| Clone | [CTD4H8] |
| Host Species | Mouse |
| Reactive Species | human. mouse. rat. |
| Isotype | IgG1 |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistology (Formalin-Fixed) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RNA polymerase II (Pol II) is an enzyme that is composed of 12 subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large sub |
| Immunogen | Immunogen: 10 repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-ser 5. Positive Control: HAP1, K562, PC3, HePG2, NIH3T3 Cells. Human testis. |
| Other Names | [DNA-directed RNA polymerase II largest subunit RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit RPB1; hRPB220; hsRPB1; POLR2; Polr2a; POLRA; Polymerase (RNA) II (DNA directed) polypeptide A 220kDa; RNA polymerase II subunit B1; RPBh1; RpIILS; RPO2; RPOL2] |
| Gene, Accession # | [POLR2A], Gene ID: 5430, NCBI: NP_000928.1, UniProt: P24928 |
| Catalog # | MBS4380656 |
| Price | $190, $340, $340 |
| Order / More Info | RNA Polymerase II/Poll II Antibody from MYBIOSOURCE INC. |
| Product Specific References | Madak-Erdogan, Z., et al. 2008. Mol. Endocrinol. 22: 2116-2127. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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